Press Releases & Company News

Cosmo Pharmaceuticals S.p.A. IPO over-allotment option fully exercised

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Canada, Japan or Australia

Cosmo Pharmaceuticals S.p.A. IPO over-allotment option fully exercised

Lainate, Italy – 15 March 2007 – (SWX: COPN) Cosmo Pharmaceuticals, a specialty pharma company that aims to become a global leader in optimised therapies for certain gastro intestinal (GI) diseases, today announced that Joint Global Co-ordinators and Joint Bookrunners Bank Sal. Oppenheim jr. & Cie. (Switzerland) Ltd. and Lehman Brothers International (Europe), have fully exercised the over-allotment option (Greenshoe) to subscribe additional 348,900 shares at the offer price. The first trading day for the additional shares on the main board of the SWX Swiss Exchange is expected to be on 19 March 2007.

Based on yesterday’s closing price of CHF 22.50 market capitalization of Cosmo, with the over-allotment option being exercised, will total CHF 312.2 million. Cosmo Pharmaceuticals S.p.A. started trading on the SWX Swiss Exchange on 12 March 2007.

Mauro Ajani, CEO of Cosmo Pharmaceuticals said: “We are delighted to see that Cosmo Pharmaceuticals S.p.A. has received such an enthusiastic reception by the stock market with a share price increase of nearly 15% in three days despite the prevailing adverse market conditions. We are thus pleased that the Joint Global Coordinators and Joint Bookrunners are exercising the full Greenshoe only a few days after launch on the SWX Swiss Exchange”.

About Cosmo Pharmaceuticals
Cosmo is a speciality pharma company that aims to become a global leader in optimised therapies for certain gastrointestinal diseases. The company’s proprietary clinical development pipeline specifically addresses innovative treatments for inflammatory bowel diseases (IBD), such as ulcerative colitis and Crohn’s disease, and colon infections. Cosmo’s most advanced development product is LIALDA™/ MEZAVANT™, a treatment for mild-to-moderate ulcerative colitis that is licensed globally to Giuliani and Shire plc. Cosmo’s proprietary MMX™ technology is at the core of the company’s product pipeline and was developed from its expertise in formulating and manufacturing gastrointestinal drugs for international clients at its GMP (Good Manufacturing Practice) facilities in Lainate, Italy. More on www.cosmopharmaceuticals.com

For more information please contact
Dr. Chris Tanner, CFO and Head of Investor Relations
Cosmo Pharmaceuticals S.p.A.
Tel: +39 02 9333 7614

Not for release, publication or distribution in the United States of America,
Canada, Japan or Australia

This document does neither constitute an offer to buy or to subscribe to shares of COSMO Pharmaceuticals S.p.A. nor a prospectus within the meaning of the applicable Swiss law. Investors should make their decision to buy or to subscribe to shares solely based on the official offering and listing prospectus. Investors are furthermore advised to consult their bank or financial adviser.

This publication may contain specific forward-looking statements, e.g. statements including terms like "believe", "assume", "expect" or similar expressions. Such forward-looking statements are subject to known and unknown risks, uncertainties and other factors which may result in a substantial divergence between the actual results, financial situation, development or performance of the company and those explicitly or implicitly presumed in these statements. Against the background of these uncertainties readers should not rely on forward-looking statements. The company assumes no responsibility to update forward-looking statements or to adapt them to future events or developments.

This document is not being issued in the United States of America and should not be distributed or otherwise transmitted in the United States or to U.S. persons (as defined in the U.S. Securities Act of 1933, as amended (the Securities Act )) or publications with a general circulation in the United States. This document does not constitute an offer or invitation to subscribe for or purchase any securities. The securities of COSMO Pharmaceuticals S.p.A. have not been and will not be registered under the Securities Act and are not being offered or sold in the United States or to U. S. persons. Securities may not be offered or sold in the United States or to U.S. persons absent registration or an applicable exemption from the registration requirements of the Securities Act.

The information contained herein does not constitute an offer of securities to the public in the United Kingdom within the meaning of the Public Offers of Securities Regulations 1995. No prospectus offering securities to the public will be published in the United Kingdom.

This document is only being distributed to and is only directed at (i) persons who are outside the United Kingdom or (ii) to investment professionals falling within Article 19(5) of the Financial Services and Markets Act 2000 (Financial Promotion) Order 2005 (the Order ) or (iii) high net worth entities, and other persons to whom it may lawfully be communicated, falling within Article 49(2)(a) to (d) of the Order (all such persons together being referred to as relevant persons ). The securities are only available to, and any invitation, offer or agreement to subscribe, purchase or otherwise acquire such securities will be engaged in only with, relevant persons. Any person who is not a relevant person should not act or rely on this document or any of its contents.

This document constitutes neither an offer to sale nor an invitation or solicitation to buy securities in Italy and does not constitute a public offering under the meaning of sections 1, item t) and 94(1) of the Legislative Decree n. 58 of 24 February 1998. The securities referred to herein cannot be offered, distributed, marketed, promoted or solicited in Italy to investors other than "Professional Investors" as defined by Articles 25 and 31(2) of Consob s Regulation No. 11522 of 1 July 1998, as amended, (including, inter alia, investment firms, ("SIMs"), banks authorized to provide investment services, stockbrokers, SICAVs, pension funds, insurance companies, entities enrolled in the register referred to in Articles 106, 107 and 113 of the Legislative Decree 385 of 1 September 1993, financial salesmen, individuals possessing the professionalism requirements referred to in Article 31(2) of the Regulation No. 11522, legal persons stating to have specific expertise and experience in financial transactions) without Consob's prior authorization. COSMO Pharmaceuticals S.p.A. intends neither to carry out a public offering of the securities in Italy nor to apply for the relevant Consob's authorization. This press release is not directed to Italian residents other than Professional Investors as defined above.

Any offer of securities to the public that may be deemed to be made pursuant to this communication in any EEA Member State that has implemented Directive 2003/71/EC (together with any applicable implementing measures in any Member State, the Prospectus Directive ) is only addressed to qualified investors in that Member State within the meaning of the Prospectus Directive.

The securities described herein will be offered publicly in Switzerland only. The information contained herein shall not constitute an offer to sell or the solicitation of an offer to buy, in any jurisdiction in which such offer or solicitation would be unlawful prior to registration, exemption from registration or qualification under the securities laws of any jurisdiction.

Stabilization/FSA

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